This was a difficult one for me. If I find one that's weird (like dragonfruit). I want to figure out how to highlight it. If it's one that I find inconvenient, maybe I don't use it quite so often. Inconvenient fruits include mangos (which have a massive pit that refuses to come out), kiwi (which have that furry outside), and pomegranate (which require skill to relieve of their treasure, and make permanent stains if you're not careful).
Then, it came to me:
Prickly pears! I've tried to work with them, really I have. Detroit has a huge Mexican population, and these are a beloved fruit from south of the border. But, as the name implies, the native version of the fruit has thorns on it. You can buy them in specialty markets without the thorns, but your trouble isn't over. The skin is inedible (as you can imagine, having just had thorns on it). The seeds - the black parts you can make out in the cross-section - are inedible, too...you can break a tooth if you don't take them out. And, the seeds are slimy and hard to work around.
For all the work that's required to work around the bad stuff, the flavor is merely...okay. It's a bit like a bland cantaloupe. I did make salsas with them, but it was so much work, and I couldn't really taste it.
So, if I were stranded in a desert, and prickly pear were the only source of food, I
might consider trying to have one. But, until that happens, I will instead use literally any other fruit.