A very general guideline is that the East and West Coasts are more liberal, while the center of the country, nicknamed "flyover country," is more conservative. the Bible Belt runs across the Deep South.
Now, within very conservative states, like Texas, the big cities like Houston, Dallas, San Antonio and Austin vote Democratic, while the rest of the State is mostly hard-core Republican. Well educated suburbs like Frisco, where I live, is Republican, but very moderate... and more tolerant of ethnic minorities and LGBTQ issues.
Here is a Red State/Blue State map. The Red States are Republican States, The Blue are Democratic States. The pink and purple States are know as "Swing States," as they don't have one dominant party.
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